DPCstruct | MC4353

Metacluster Properties and Pfam Annotations

Number of structural domains33
Mean domain length (aa)92 ± 9 aa
Standard deviation of domain lengths9.24
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score83.08
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)26.02
Pfam Score97.62
Assigned Pfam label(s) PF12660- CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1X7VQM1 16-115 EFDFSIAENCLSFVVNNLAQVEKCPICSEIILYCNPLSGSCSNNHCWERCVLTQCIVSQFAESMSCSICNKLVNITRGGWLGHVLKT…
A0A151MFR4 141-234 VLIGHILKKMNKQTFPEHCSLCKEILPFTDRKQAVCSNGHIWLRCFLTYQSCQSLVYRRCLLHDSIARHPTPEDPEWIKRLLQGPCT…
A0A7G5JJL0 1028-1111 None
H1V3W6 111-204 None
A0A6J8DK04 505-600 None
A0A0V0J7Z2 241-320 None
T1F0Q6 53-143 None
A0A1V8SKY6 605-703 None
A0A0M8MTU0 783-858 None
A0A5K3FFK2 443-540 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.