DPCstruct | MC43505

Metacluster Properties and Pfam Annotations

Number of structural domains21
Mean domain length (aa)74 ± 5 aa
Standard deviation of domain lengths4.87
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score81.16
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.92
Mean intra-cluster local Distance Difference Test score0.91
Mean intra-cluster sequence similarity (%)47.57
Pfam Score95.83
Assigned Pfam label(s) CL0020- PF15443

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6P8H1I8 1-74 MKTHLTSAAGILALLEEGESDLKVYALDKLNVIMDDFWAEISESVAKIEVLYEDETFKHRKLSALVASKVRRKI
A0A086M9F3 25-99 APPASSAAGVLALLHERDSALQAASLHRLLQMIDVWWTEIADYLADIEALYEDESFAERQLAGFIASRVYFHLEE
A0A183MXF4 1-86 None
A0A086Q4Y7 24-93 None
A0A0V1Q0K8 1-72 None
A0A6G3MJ61 5-82 None
A0A1S8VI56 1-83 None
A0A446J957 1-79 None
A0A5B7D2B2 1-76 None
A0A1Y3ECS7 458-524 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.