DPCstruct | MC435

Metacluster Properties and Pfam Annotations

Number of structural domains43
Mean domain length (aa)94 ± 8 aa
Standard deviation of domain lengths7.79
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score78.38
Mean fraction of residues predicted as intrinsically disordered0.49
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)31.72
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A521S1S1 3-90 EKGESKVTVDPEEIRRWAEARGGKPAVVKGTDILRINFPGGAEEELQDIPWEEFFQKFEEKGLAFLYQEKKADGEPSTFNKFVSRETV
A0A7C2ZAN4 17-109 GCRPGETLATRELAVIQRWAAERGAVPATVPGTEHEGRPGVLALDFPGFKEKGLQPISWEEWFKTFQVRHLWFLYQERLRDGRPSNF…
A0A285F1T3 156-248 None
A0A848PXB1 3-96 None
U4V8F3 36-140 None
A0A0G1MN52 2-101 None
A0A522T5J6 2-88 None
Q2IPC2 5-96 None
A0A3L7BV85 292-388 None
A0A143PK42 34-143 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.