DPCstruct | MC43386

Metacluster Properties and Pfam Annotations

Number of structural domains111
Mean domain length (aa)264 ± 56 aa
Standard deviation of domain lengths55.74
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score90.48
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)26.96
Pfam Score98.25
Assigned Pfam label(s) CL0392- CL0254- CL0059

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Q7UUN6 240-570 QVAAEMRDYILQALKELVGQWADVYTAQFIQYNPTFKTTYGFPAGYGSVQNLNDHHFHYGYFLRAAAAIGRYDRPWLDGYLPFFDEL…
G2WSD1 126-418 LGKLKQAFARFAANKQKFPLVYERSWGGLVSSASYVTGNSGADFGNTDYNDHHFHYAYHVLAAAVIGHLDPSWIPENMAYVNLLVRD…
A0A7S1VDR7 29-261 None
Q2GSD7 505-695 None
G8LUU1 565-844 None
A0A3P6CL11 110-354 None
A0A081AJ76 34-287 None
A0A7L5ADR0 725-1005 None
A0A6G0SBT6 182-474 None
A0A2G8LIY1 5-278 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.