DPCstruct | MC43361

Metacluster Properties and Pfam Annotations

Number of structural domains116
Mean domain length (aa)124 ± 22 aa
Standard deviation of domain lengths22.49
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score90.08
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)27.92
Pfam Score80.40
Assigned Pfam label(s) CL0105- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C5UT80 389-515 LPPGFRPALRFKTMVAQVRDFPPGSSISYGRTYRTSGQQRIAVLPVGYADGFRRAPHHWGEVLIRGRRAPIVGRVCMDYTMVEVSHI…
A0A6M1HWI2 44-132 MTLKSSLIAVREHQAGEAVGYGGTWISPRDTRLGVVAMGYGDGYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPQAQDKAGDA…
A0A837Q164 3-90 None
A0A3L7PMW3 199-350 None
A0A7L5AJH0 53-171 None
A0A356C050 25-160 None
W7ZJ88 110-229 None
A0A2M8Q114 729-855 None
A0A3P3VYN0 496-616 None
A0A7Y7DFF3 284-413 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.