DPCstruct | MC43323

Metacluster Properties and Pfam Annotations

Number of structural domains55
Mean domain length (aa)148 ± 35 aa
Standard deviation of domain lengths35.39
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score77.62
Mean fraction of residues predicted as intrinsically disordered0.40
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)24.67
Pfam Score89.05
Assigned Pfam label(s) CL0172- CL0361- CL0131

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
F4PHC7 2-215 NKEIEEFLKQNKSFVYNKETNRIKCEVTNHEMMPKIEQLKQHLTSKKYKMTIAYTFDYTKYEPYIIQSRNNEKIEEEGEEEEEEEED…
A0A5D6Y621 247-378 IEALVGSLDDLAFIGDGSRVRCATTGHEMKADVDVVRAHLHGKRYVRAKLKRQSFASFAPMFAAHPDEKKAHLLWCRVTETEHPRDV…
A0A7E4VNY3 5-153 None
A0A3Q0IY03 93-295 None
D8RXY1 6-201 None
A0A553MVK8 18-181 None
A0A340XJ98 7-198 None
L8YC44 42-170 None
T1EKX2 3-94 None
R7TRJ5 4-203 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.