DPCstruct | MC43299

Metacluster Properties and Pfam Annotations

Number of structural domains5
Mean domain length (aa)90 ± 4 aa
Standard deviation of domain lengths3.76
Length coefficient of variation0.04
Mean AlphaFold2 pLDDT confidence score88.24
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.89
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)51.47
Pfam Score100.00
Assigned Pfam label(s) CL0039

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y7X528 219-301 MQRNWIGKSRGVEMDFPVDGSDLKIKIFTTRPDTLFGATFVCVAPIHPIADIIMDDKNALNDVKSFYGNEEEKRGVFTGKYVV
A0A378BL10 1-94 MQRNWIGRSEGVEISFDVNDYADKLTVYTTRPDTFMGCTYLAVAAGHPLAQQAAANNPALATFIDECRNTKVAEADMATMEKKGVDT…
A0A378DIG6 71-161 None
A0A3S4ZWG1 57-145 None
A0A2B4R2S6 475-566 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.