DPCstruct | MC43245

Metacluster Properties and Pfam Annotations

Number of structural domains532
Mean domain length (aa)116 ± 20 aa
Standard deviation of domain lengths20.46
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score76.35
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)17.46
Pfam Score95.30
Assigned Pfam label(s) PF01684- CL0012- CL0117- CL0192- CL0001

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E2BID2 87-206 None
A0A8B6F5S6 1-110 None
A0A8B6EWE8 91-191 None
A0A8B6EV30 233-329 None
A0A6P7U1I7 7-116 None
A0A402FMX9 43-163 None
A0A0M4E3E0 13-140 None
A0A6J1PR51 5-125 None
A0A1D2MCP8 1-169 None
A7SV14 202-325 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.