DPCstruct | MC43245

Metacluster Properties and Pfam Annotations

Number of structural domains532
Mean domain length (aa)116 ± 20 aa
Standard deviation of domain lengths20.46
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score76.35
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)17.46
Pfam Score95.30
Assigned Pfam label(s) PF01684- CL0012- CL0117- CL0192- CL0001

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A654HC80 29-144 SLFCILVGLSCAAALECYECSQVAGNTGPCTSTRRTCRVSQDACISFVQYRTPDFWTILSERRPFISKGCTSKMECASQVDFFRDRC…
A0A8B6H4T1 1-102 ISCHLCRGPKFICERSYASAVCPDPSQQFCINDVENLKDGSRYVTRRCATKAECDKDWITESSYRNECSHYNVVILQDAHFECSFCC…
A0A6P8IDF1 65-209 None
A0A2G8LMI6 4-170 None
A0A803JA50 62-169 None
A0A803JS12 202-316 None
A0A2D0QHL7 6-146 None
A0A7M5UEL9 4-99 None
A0A7M5V7E0 7-158 None
A0A067RM99 6-104 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.