DPCstruct | MC43222

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)93 ± 10 aa
Standard deviation of domain lengths9.74
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score89.83
Mean fraction of residues predicted as intrinsically disordered0.35
Mean length-normalized TM-Score0.87
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)38.38
Pfam Score100.00
Assigned Pfam label(s) CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2D4HIC6 53-156 VFTTQLNSIPGSAVCAFNMEDIEKVFKGRFKEQKTPDSVWTAVPEDKVPRPRPGCCAKHGPAEAYKTSIDFPDETLSFIKSHPLMDS…
A0A8B6DUF0 375-466 YGVFITTTGTPASAICAFNLSSIDAALEGSFKEQTSANTFWTEVTTVPTPRPGQCTNDSMSLSESVLQFIADHPLMHKTVQPMYEKP…
A0A4W5MVF2 6-106 None
A0A1S3PW25 1-86 None
A0A1A9WXA1 38-115 None
A0A673KVU2 217-318 None
A0A2A3EPW6 264-341 None
A0A8B6CR39 171-262 None
A0A132A6C9 65-144 None
A0A6H5IKD0 68-164 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.