DPCstruct | MC43196

Metacluster Properties and Pfam Annotations

Number of structural domains52
Mean domain length (aa)376 ± 61 aa
Standard deviation of domain lengths61.33
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score71.61
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)23.37
Pfam Score84.32
Assigned Pfam label(s) PF08295- PF16879

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6S8VSI8 1-405 MDFSSCARHTPSYRALPMSLAQPRSHRRLSLELAVLNDMCINVSSEKACGFMHPKKDKCEQELFQLEDQRYELDMIIDANSACVAVL…
T0LBL6 15-301 EASLVIERLDFLITSLEIVYSNLGTDELSIKDIGMSPGIIKEVLKNIYDESASEILEGILINPKKAIPILIKRLYAVNKDLREKLRQ…
M4CWY0 75-392 None
A0A6J3CBY4 18-490 None
A0A811MYK2 545-861 None
A0A7N0REP5 465-818 None
A0A0C2MR01 202-589 None
A0A0K0EKT0 1039-1467 None
Q6FNH7 264-684 None
A0A5D3DIK1 444-781 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.