DPCstruct | MC43177

Metacluster Properties and Pfam Annotations

Number of structural domains38
Mean domain length (aa)224 ± 50 aa
Standard deviation of domain lengths50.38
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score91.27
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)26.75
Pfam Score100.00
Assigned Pfam label(s) CL0286

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H0YC33 271-548 NMSEFATYLKVGITSIILKMLEDGFFEGDIILKEPVKGIKLVSLDLTCKKPVMETLGGRKLSSLDMNWEFFERAKQYFSQVCEPSPE…
A0A838KM98 25-265 LAEISTLLKVGTTALVLAMIEERVISADLAIDGPVSALHAVSHDPTLTHLITLKDGRSMTALDLQEIYLELARHHTAERYGDDADPD…
A0A3D0TW66 4-254 None
A0A0S7ZQI5 179-438 None
A0A2Z5QS05 4-203 None
A0A2Z5QU87 700-1015 None
M5RUF1 218-441 None
A0A6L5C6N6 483-719 None
A0A1F5BWQ1 145-407 None
A0A0K8QEJ5 450-689 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.