DPCstruct | MC43169

Metacluster Properties and Pfam Annotations

Number of structural domains28
Mean domain length (aa)181 ± 21 aa
Standard deviation of domain lengths21.22
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score74.38
Mean fraction of residues predicted as intrinsically disordered0.45
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)41.30
Pfam Score75.73
Assigned Pfam label(s) CL0020- PF18004

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0C2M8F1 5-197 KSAFVAAGMVLVQRNEKTTESFRDIRSQLTSLCHDRRAEAVAKLGAYVGLGIMDAGCRNQTLAFKTLQGHTRMPSIVGFLVFQQFWY…
A0A287GHB0 185-343 GISCAGTGLSDAISLLEPLTSDVVDFVRQGALIAMAMVMIQTNESFDSRVGTFRRQLEKIILDKHEDTMSKMGAILACGILDAGGRN…
A0A444U653 808-983 None
A0A813GU74 60-252 None
A0A812S8Z6 157-346 None
A0A0R3Q5T7 55-223 None
A0A830CGF2 475-654 None
J9DRM3 130-335 None
R4XB38 662-848 None
A0A6G3MEK2 82-297 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.