DPCstruct | MC43156

Metacluster Properties and Pfam Annotations

Number of structural domains1504
Mean domain length (aa)115 ± 23 aa
Standard deviation of domain lengths22.97
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score78.56
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)15.98
Pfam Score94.18
Assigned Pfam label(s) PF01288- PF09309- PF06732- CL0123- PF12258

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4S8LTG8 2-85 None
A0A7X4E200 475-560 None
A0A5M3ZC64 231-357 None
A0A395I6R3 259-405 None
A0A1Y2NZA1 345-437 None
A0A2A6BRU5 241-392 None
A0A452ZIS1 406-530 None
A0A452ZI88 187-287 None
A0A452ZI47 69-181 None
J0LCR2 4-139 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.