DPCstruct | MC43156

Metacluster Properties and Pfam Annotations

Number of structural domains1504
Mean domain length (aa)115 ± 23 aa
Standard deviation of domain lengths22.97
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score78.56
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)15.98
Pfam Score94.18
Assigned Pfam label(s) PF01288- PF09309- PF06732- CL0123- PF12258

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7S0ML11 23-134 NEGGPNSVGDGHVPSKILKDLVFAITGNFGKDRDSVFTMIKELGAGDISPTVHKRVDFLLADDDAVSSETKHIRKAVKYGVQVVSLK…
H3C8W0 70-174 PPGAKPCSQHIMSVTGFVDADRDDLKLMAYLTGARYTGYLCRSNTVLICKEPVGLKYEKAKEWKIPCVNAQWLCDVLLGNFEALRQI…
A0A482VEE4 374-480 None
W6Y0J9 2-106 None
A0A2W1BSD6 321-416 None
A0A2W1BR07 1-162 None
A0A6V7PCS8 359-461 None
A0A2W1BL50 7-127 None
B5VL86 2-107 None
A0A812PCG5 59-155 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.