DPCstruct | MC43154

Metacluster Properties and Pfam Annotations

Number of structural domains56
Mean domain length (aa)276 ± 78 aa
Standard deviation of domain lengths78.49
Length coefficient of variation0.28
Mean AlphaFold2 pLDDT confidence score83.57
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)27.39
Pfam Score65.44
Assigned Pfam label(s) PF06883- PF04561- CL0410- PF04563- PF04567

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0W8DRE4 19-328 None
A0A2P5VWZ4 176-346 None
A0A6J5TVR6 372-638 None
A0A452YHN1 34-445 None
A0A2G8JQQ5 3-242 None
A0A1D6KX16 220-551 None
Q8II17 566-773 None
E6YCT1 6-271 None
L5M8P2 50-297 None
A0A2U3Z4F4 257-519 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.