DPCstruct | MC43139

Metacluster Properties and Pfam Annotations

Number of structural domains928
Mean domain length (aa)245 ± 57 aa
Standard deviation of domain lengths56.87
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score81.74
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)14.99
Pfam Score68.52
Assigned Pfam label(s) PF01267- PF12449- CL0108- PF08676- CL0046

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A094BD12 20-322 None
A0A182H2L2 4-288 None
A0A847H251 169-324 None
A0A0J8QW80 21-233 None
K8PA91 13-297 None
A0A2G6TFV1 107-294 None
A0A7V2X6D6 2-208 None
A0A388K4M5 463-721 None
A0A0K1EJJ0 11-159 None
A0A5A9P1D2 1-238 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.