DPCstruct | MC43139

Metacluster Properties and Pfam Annotations

Number of structural domains928
Mean domain length (aa)245 ± 57 aa
Standard deviation of domain lengths56.87
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score81.74
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)14.99
Pfam Score68.52
Assigned Pfam label(s) PF01267- PF12449- CL0108- PF08676- CL0046

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2A2KQS6 293-571 None
A0A835RH81 19-314 None
A0A3R9PCZ9 231-425 None
A0A7T7FRM2 73-326 None
A0A7V7T386 16-226 None
A0A2T1I3H6 14-231 None
S4MUV8 587-851 None
C1FHV5 31-280 None
A0A2V7J8L2 84-357 None
B6UCZ5 79-391 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.