DPCstruct | MC43139

Metacluster Properties and Pfam Annotations

Number of structural domains928
Mean domain length (aa)245 ± 57 aa
Standard deviation of domain lengths56.87
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score81.74
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)14.99
Pfam Score68.52
Assigned Pfam label(s) PF01267- PF12449- CL0108- PF08676- CL0046

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A846AAP4 12-182 None
A0A2I5JX24 9-200 None
A0A3B6LGQ0 3-329 None
A0A3S4K3G9 1-200 None
A0A0G1MKI1 14-213 None
A7HRY0 1-180 None
A0A1M6Q112 6-314 None
H2PM00 122-295 None
A0A816SMF0 584-830 None
A0A2V2U8E3 46-295 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.