DPCstruct | MC43139

Metacluster Properties and Pfam Annotations

Number of structural domains928
Mean domain length (aa)245 ± 57 aa
Standard deviation of domain lengths56.87
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score81.74
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)14.99
Pfam Score68.52
Assigned Pfam label(s) PF01267- PF12449- CL0108- PF08676- CL0046

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1K1MKT9 1-238 MKKHTAKITSKSIEQSGLPSDFKKAIAEYIWNGFDANASVVELDFDANAVGYINSFSISDNGFGINLGRIDETFGQFMDSHKTKTFD…
A0A356KLY4 5-163 TYPECLAAVLENAFDQVREGPCRSIQLEILGESFRVRDDGEGLPVHPHPFSKRPLLEVILMGPRRGEPNTLARVTKCCLWVEVETET…
A0A2E8RAW9 8-222 None
A0A835XU63 17-225 None
A0A5D3D2J3 268-563 None
A0A6A5ZXK6 10-230 None
A0A7Y4TSG6 72-346 None
A0A4S4DEP1 154-395 None
A0A821RZU8 1-203 None
A0A1H6J790 8-181 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.