DPCstruct | MC43110

Metacluster Properties and Pfam Annotations

Number of structural domains82
Mean domain length (aa)133 ± 25 aa
Standard deviation of domain lengths24.82
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score85.74
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)17.66
Pfam Score92.42
Assigned Pfam label(s) PF18406- PF06924

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7S1XZB8 18-130 FAAVLPLPKGFEETREGEDYREVIDWQSANWGTKWDLEDTELTVVAEGTKATAKFETAWSPPQEWFAFVVRKYPRLRFELAYQEGGM…
A0A373XYT1 3-160 NHITTRIKITGDPEAVKRVLNKIKNDEFGMGTIDFEKIIPMPKNIFKGNLGVRERELYGNNNWYDWSVANWGTKWNAYGFDPNTDYS…
A0A7B8FZY0 47-179 None
A0A3G4RTQ2 18-136 None
A0A517NTB5 1-158 None
I7J1I8 1-141 None
A0A843FJE9 71-176 None
A0A5C1ISX8 1-144 None
A0A2V2BFR6 2-116 None
A0A3P5HE31 11-122 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.