DPCstruct | MC43066

Metacluster Properties and Pfam Annotations

Number of structural domains426
Mean domain length (aa)168 ± 30 aa
Standard deviation of domain lengths29.81
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score89.07
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)28.83
Pfam Score100.00
Assigned Pfam label(s) PF01425

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Z0A1M0 19-162 IAVIPFDEQAVEESPTLKGQPVAFKDIVDVAFVPTTCGTNVDVGRIPIEDAPVVQRLTAKGALPVAKANLQEFSYGILGDASAYGRV…
K9IEG3 31-215 DQIEADQAVLNDFVTINRDEALKQAQAIDEKGVDPDNLWAGIPIAVKDNIVTKGLKTTASSKMLSNFTPIYDATVIERLKANDVIVI…
A0A0K0E0M2 1179-1369 None
A0A814VKG4 191-435 None
A0A5C6SZ96 105-288 None
A0A0N0P4Y2 15-274 None
G5HJH7 440-615 None
A0A542MX95 408-560 None
A0A5C4M1I6 108-276 None
A0A0V0R127 157-337 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.