DPCstruct | MC43038

Metacluster Properties and Pfam Annotations

Number of structural domains69
Mean domain length (aa)122 ± 22 aa
Standard deviation of domain lengths22.28
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score78.37
Mean fraction of residues predicted as intrinsically disordered0.41
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)31.10
Pfam Score98.78
Assigned Pfam label(s) PF04800- PF05030

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
K8EY85 8-129 NRFSTSPHHHHTSSSFEKNTLREGEHFKKVIGFKPSKIASSQGASYISNPWRLRDATASGEVNHWENPLQGYVSFGSEGKVPKTLEF…
G2XJ19 68-190 RIQDGSEDVPYIQAATVSGAPMELQGRTVRIYQETKPATQSGNWQGHHWRMDWDILPKGHRWENPLMGWQSSGDMMQGTKLNFKTKE…
A0A7W8LVX3 2-82 None
V5IK22 27-185 None
A0A368A5I5 2-82 None
A0A7R9A7N9 632-762 None
A0A0D8X956 32-167 None
A0A6A7ZUD2 40-198 None
A0A7R9PWG7 69-198 None
A0A182FHE4 591-723 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.