DPCstruct | MC43033

Metacluster Properties and Pfam Annotations

Number of structural domains81
Mean domain length (aa)102 ± 14 aa
Standard deviation of domain lengths14.11
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score84.37
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)20.52
Pfam Score81.50
Assigned Pfam label(s) CL0408- PF14693- CL0733

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
K8EMZ7 91-194 KILRLIAHDREKAGRLSANRARKDGFIPCAVFKQGEIEKTSEVCAVSEREVEKLLRKFTKYGLRTKLIDIVLDDGKRTVKAIPQQIQ…
A0DGI5 128-228 KKVVLPAKRVRSLDDHIIGLWKQHEVAVVIEGRDEFEDIDIVLDYYQVAAVKRRICANVAPIYIRIPGHDGDIRCTLGEIIKDPKSG…
A0A3A0AVY4 4-99 None
A0A7J6LPQ7 362-464 None
A0A6V7PT10 381-494 None
A0A6J7I124 3-95 None
A0A6A6L6B2 58-172 None
A0A7S3KF99 105-202 None
A0A371JKK6 29-123 None
A0A7S3N8T4 107-206 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.