DPCstruct | MC43020

Metacluster Properties and Pfam Annotations

Number of structural domains6798
Mean domain length (aa)134 ± 23 aa
Standard deviation of domain lengths23.44
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score78.27
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)11.32
Pfam Score85.22
Assigned Pfam label(s) PF08736- PF01412- CL0020- CL0330- PF00621

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1I8CWB8 334-494 None
A0A1I8CV61 5-133 None
A0A1I8CRD7 40-192 None
A0A1I8CN76 12-178 None
A0A1I8CGB3 179-343 None
A0A1I8CDB5 497-617 None
A0A1I8C718 229-342 None
A0A1I8C5N4 280-429 None
U3KCK3 271-409 None
U3KAP0 83-219 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.