DPCstruct | MC43020

Metacluster Properties and Pfam Annotations

Number of structural domains6798
Mean domain length (aa)134 ± 23 aa
Standard deviation of domain lengths23.44
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score78.27
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)11.32
Pfam Score85.22
Assigned Pfam label(s) PF08736- PF01412- CL0020- CL0330- PF00621

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y2BED0 21-160 None
A0A444IZI7 243-364 None
A0A0S7L3K7 257-372 None
A0A0S7KWG1 18-145 None
A0A0S7KTY7 47-152 None
A0A060HGZ0 224-384 None
A0A2D6ST49 1-149 None
D8M1H8 1-113 None
D8M0R1 95-233 None
D8LYR8 17-121 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.