DPCstruct | MC43020

Metacluster Properties and Pfam Annotations

Number of structural domains6798
Mean domain length (aa)134 ± 23 aa
Standard deviation of domain lengths23.44
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score78.27
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)11.32
Pfam Score85.22
Assigned Pfam label(s) PF08736- PF01412- CL0020- CL0330- PF00621

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4U1FRN4 147-257 None
A0A7R9TYW4 221-362 None
A0A661PGF6 4-129 None
A0A5K4F5R0 112-240 None
A0A5K4F5P3 8-136 None
A0A5K4F4B9 11-168 None
A0A5K4F2U0 214-349 None
A0A5K4F1I1 3-130 None
A0A5K4F0B6 1337-1475 None
A0A5K4ELG8 1750-1865 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.