DPCstruct | MC43020

Metacluster Properties and Pfam Annotations

Number of structural domains6798
Mean domain length (aa)134 ± 23 aa
Standard deviation of domain lengths23.44
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score78.27
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)11.32
Pfam Score85.22
Assigned Pfam label(s) PF08736- PF01412- CL0020- CL0330- PF00621

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A066VCY6 1-125 None
E2BZN3 30-185 None
A0A1Q9C2E0 54-203 None
A0A2I0LAY8 22-171 None
A0A1S8W5J0 129-267 None
A0A1S8W0C0 449-562 None
A0A1S8VTU4 181-318 None
A0A821ATQ2 46-183 None
A0A1S8VPI7 281-428 None
A0A1S8VGS1 100-246 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.