DPCstruct | MC43020

Metacluster Properties and Pfam Annotations

Number of structural domains6798
Mean domain length (aa)134 ± 23 aa
Standard deviation of domain lengths23.44
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score78.27
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)11.32
Pfam Score85.22
Assigned Pfam label(s) PF08736- PF01412- CL0020- CL0330- PF00621

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7S2SVR3 17-137 EVIQVMLPRGMAVEMRGPVLQLRGRGRILSKVWKTVWLSLTAYALVLRKGELEVSKLLAAVDLRQITAVEKSSNVRYGFLITSAANE…
A0A177VGZ4 782-907 PVLAGWVYVEDRKKKWAKRWLELREHSLYHAKSEKGKDEVFICSLSTFDVYLVDTGKIKTPRPHAFAIRSQNSITMFEKPDQDYVHY…
A0A034VGE7 4-116 None
A0A7S0LVA4 9-126 None
A0A7S0LV29 52-190 None
A0A1X6PLF2 9-101 None
A0A1X6PHE8 30-136 None
A0A7S1XY75 1-144 None
A0A7S1UK28 23-195 None
A0A7R9Q3Q8 271-412 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.