DPCstruct | MC42978

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)81 ± 3 aa
Standard deviation of domain lengths3.41
Length coefficient of variation0.04
Mean AlphaFold2 pLDDT confidence score76.04
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)73.50
Pfam Score87.27
Assigned Pfam label(s) CL0409- PF00786

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
T1NW86 1-72 HVAHVTFDRRQGFLGLPVEFELQIPCPAPSASTSVFGVSPESMQCGYDDRGNSVPKILLLMQEWLYTQDGLK
A0A2K3M780 1-84 MDISSPTNVRHVAHVTFDRFNGFLGLPDEFEPDFPRRPPSASATVFGVSTESMQLSYDSRGNSVPTILLLMQRHLYVQGGLQVE
A0A1D1Y3G7 24-101 None
A0A2U1PZ12 98-177 None
A0A6A6L4Y7 1-80 None
A0A0A9NG50 1-88 None
A0A453PA28 48-128 None
A0A5N5FXM5 111-190 None
A0A5P1E1I8 15-98 None
A0A7J8ZCQ5 108-189 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.