DPCstruct | MC42977

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)104 ± 21 aa
Standard deviation of domain lengths21.42
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score78.87
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)51.32
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J8V5U8 3-80 RRVLVHLPSGEVVSSYSSLEHILRGLGWERYYGGDPDLYQFHKHSSIDLISLPKDFSKFCSVHMYDIVVKNPNVFHVR
T1NKM5 1-97 GVWVFRKDGVMELAQEASSRKALVYLPANETMRSLPALERRLGSLGWERYYEDRALVQLHRRDGSLDLISLPRDFSQFRSIHMYDVV…
A0A1P8BBN7 37-144 None
A0A4S8I7F1 9-66 None
A0A2R6X066 57-204 None
A0A834X0X3 65-176 None
A0A2S3HNE2 142-251 None
A0A453MSG1 1-68 None
A0A835KQV6 68-182 None
A0A835KYC6 1-100 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.