DPCstruct | MC42976

Metacluster Properties and Pfam Annotations

Number of structural domains27
Mean domain length (aa)190 ± 32 aa
Standard deviation of domain lengths32.47
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score89.93
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)71.76
Pfam Score97.50
Assigned Pfam label(s) PF01405- PF00421

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A4N2W3 20-244 YGPGIWVSDPYGLTGRVQPVNPAWGVEGFDPFVPGGIASHHIAAGTLGILAGLFHLSVRPPQRLYKGLRMGNIETVLSSSIAAVFFA…
T1NHN7 16-242 GAEGFDPFVPGGIASHHIAAGTLGILAGLFHLSVRPPQRLYKGLRMGNIETVLSSSIAAVFFAAFVVAGTMWYGSATTPIELFGPTR…
A0A453DVM0 1-133 None
A0A7J9KP56 2-182 None
A0A830C908 13-183 None
A0A445EVY0 28-245 None
A0A650F2R9 2-182 None
A0A7J7L242 113-310 None
A0A7J7LK22 130-337 None
B9SH38 162-287 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.