DPCstruct | MC42954

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)152 ± 12 aa
Standard deviation of domain lengths11.87
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score86.59
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)22.12
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4T8IHU1 4-147 ATAHMMAILGIHPETYLVRITSLEYVNYRRMLISGHTHTVAKIEDPYDLKPHPFLPGLMLPTIKPSQRLGLECLNVVYTNSGISLLK…
A0A828N451 12-175 SYRNADLIKENYITEKVLSIFNIKRDFVAVRIQSNQFTDLKNKTIQGHKDTVAKVIDWYNPQKNAFGIMMGTPRRSADIAKEESRNA…
A0A3M2UUP5 22-157 None
A0A0S4UUD5 112-273 None
A0A228PYT2 334-489 None
A0A1X7AKX4 47-206 None
A0A2J6HQK7 6-131 None
A0A3S8ZSS3 123-283 None
A0A5K6V5W1 55-214 None
A0A1I1Y109 46-190 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.