DPCstruct | MC42945

Metacluster Properties and Pfam Annotations

Number of structural domains38
Mean domain length (aa)197 ± 35 aa
Standard deviation of domain lengths35.04
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score88.03
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)39.89
Pfam Score86.23
Assigned Pfam label(s) PF00547- PF00699- PF18473

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A538QE29 2-188 RLVPREIDKLLLHQAGVLAQKRLARGVRLNYPEAVALIATQLQVMDGVPELVTEVQVEGTFPDGTKLVTVHHPIVADHGDLALALYG…
A0A430FLE9 70-291 MRLTPRETDKLMLYLAGQLAKDRKSRGVKLNYVEAIALITSECVERAREGATVAELMQYGRTLLKPEDVMDGVAEMLEVVEVEATFP…
A0A6P4ZTS8 12-215 None
A0A5J6JMM7 1-224 None
A0A2T7PPG9 312-518 None
A0A6A3B592 1-186 None
C3ZHU4 1-137 None
A0A7W0P3L2 13-189 None
A0A438DIZ0 12-219 None
A0A1H3IM81 3-232 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.