DPCstruct | MC42934

Metacluster Properties and Pfam Annotations

Number of structural domains166
Mean domain length (aa)180 ± 39 aa
Standard deviation of domain lengths39.40
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score84.19
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)22.35
Pfam Score99.53
Assigned Pfam label(s) PF04114- CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5N5TI18 122-313 NYYPNCDARVWLRSCTHPVEKPISGIQIGVIPTWLNGSLIRNGPGRIQVGKDTYNHLFDGSALLHRFHFKDGEVKYSNKFLKSSSYL…
R8BP22 295-463 VFRGMNKPSRFEGDIFDLEVTGQIPKEINGTFYRVQPDARFPPVFEDDIHFNGDGSVTAIRIADGHADFKQRYVRTDRYTHETAARR…
A0A811R1I9 3-146 None
A0A835J584 338-495 None
A0A7I8KIT2 46-216 None
A0A668S7F6 7-145 None
A0A7W1MAS0 37-205 None
A0A7I7P124 36-191 None
A0A1J9RSE7 31-181 None
A0A812Z5Q4 3-176 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.