DPCstruct | MC42892

Metacluster Properties and Pfam Annotations

Number of structural domains42
Mean domain length (aa)55 ± 6 aa
Standard deviation of domain lengths5.98
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score75.55
Mean fraction of residues predicted as intrinsically disordered0.64
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.87
Mean intra-cluster sequence similarity (%)50.95
Pfam Score100.00
Assigned Pfam label(s) CL0023

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A822HLA6 3-52 IEEVKSTTKTQRISAHSHVKGLGLNDEQRAIRIAGGLVGQEQAREAAGIV
A0A7J7LAL8 2-56 QIEEVQSTTKKQRIATHTHIKGLGLQPNGNAVPMAAGFVGQVGGREAAGLVVDMI
A0A6V7PPK6 3-63 None
A0A453DU39 84-133 None
K7H8B2 1-59 None
A0A6P5H298 57-109 None
A0A7S4NC64 3-55 None
A0A842YTD9 1-47 None
A0A0N4W949 685-746 None
A0A4Z2HFS5 1-59 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.