DPCstruct | MC42854

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)72 ± 4 aa
Standard deviation of domain lengths3.97
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score85.98
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.94
Mean intra-cluster local Distance Difference Test score0.91
Mean intra-cluster sequence similarity (%)49.16
Pfam Score100.00
Assigned Pfam label(s) CL0172

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A820H6M9 74-156 RYGSTGPILYIGSLDQAIQDSVCASREERRPLAIYLHNDRSVCANVFCAQVLAGETTIEYLANNYVVWAWDVTSDANRTRYRK
A0A2I0TP91 89-160 DCHPVYFIGSLEAAFQEAFYGKARDRKLLAIYLHHDESVLTNVFCSQMLCAESIVSYLSQNFITWAWDMTKE
A0A817TLZ2 25-94 None
A0A820ZW70 78-143 None
A0A8B6BIP5 199-271 None
A0A1U7TNA5 331-400 None
A0A821UTA5 52-127 None
A0A819AX67 57-128 None
A0A818YE32 448-516 None
A0A814EHA2 124-192 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.