DPCstruct | MC42832

Metacluster Properties and Pfam Annotations

Number of structural domains3698
Mean domain length (aa)170 ± 36 aa
Standard deviation of domain lengths35.85
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score78.23
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.24
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)21.22
Pfam Score84.21
Assigned Pfam label(s) CL0213- PF00057- PF06119- CL0489- CL0550

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A3C8Q0 219-395 None
A0A183A7G9 792-992 None
A0A4Y2KVE8 32-195 None
A0A6B2LAH3 121-300 None
A0A4Y2KUN5 40-205 None
A0A4Y2KH51 107-293 None
A0A814IFY3 450-579 None
A0A814KXD3 424-562 None
A0A067L3D2 114-224 None
I4DMZ2 7-139 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.