DPCstruct | MC42832

Metacluster Properties and Pfam Annotations

Number of structural domains3698
Mean domain length (aa)170 ± 36 aa
Standard deviation of domain lengths35.85
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score78.23
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.24
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)21.22
Pfam Score84.21
Assigned Pfam label(s) CL0213- PF00057- PF06119- CL0489- CL0550

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
K7FK70 20-167 NCSNVTPNTFLCKCNKDFTGPFCEEPVEHCISQPCLNGGICQNNEHGYVCECLAGYFGHDCEADVNECSSRPCQNGATCIDMSNDVT…
A0A8B6GM81 75-235 INECSSSPCHQGTCQDNINGYSCTCNSGYTGSNCELDINECSSSPCHHGTCQDNINGYSCTCSSGYTGSNCELDINECSSSPCHHGT…
A0A7M5V309 130-346 None
A0A3S1B642 385-524 None
A0A3S1B5R8 232-410 None
A0A3S1BDH0 133-346 None
A0A7M5U9K6 344-526 None
A0A7M5UEU2 45-242 None
A0A7M5URS7 2-162 None
A0A7M5UYL7 677-864 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.