DPCstruct | MC42829

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)144 ± 19 aa
Standard deviation of domain lengths19.40
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score81.74
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)41.51
Pfam Score93.75
Assigned Pfam label(s) PF17741- CL0016

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
K7FG54 12-173 LSSAIQLIQDLMAYEVRPALLKGLVELLKPPGTEAAKGKGKILEELVTHHLAEPLSVHVQQAAAAKTIGILAKDSTKLAEELIQLGA…
A0A194AMI0 3-150 YDVSQSILKQLVTKLRPAKEDTIKRPEILEDPEIPKINAPLPVFVQQAAAAKTIGILSRESNEIAEKLIQLRVTHNLLYSMGNMDYA…
A0A813U0M6 413-577 None
A0A6P7DLD8 22-170 None
A0A498NR65 155-311 None
A0A7J5ZSQ0 471-631 None
A0A819TT03 36-195 None
A0A3M6UXE2 441-600 None
W5M4L3 58-175 None
A0A815CWZ4 6-141 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.