DPCstruct | MC42824

Metacluster Properties and Pfam Annotations

Number of structural domains66
Mean domain length (aa)144 ± 20 aa
Standard deviation of domain lengths19.97
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score91.43
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)24.62
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C2FXJ9 20-172 LCPQLVPKPLWGVSLAKLVRMRTSELIRLGLEPGVVGELKSFWLALPRDKCVVCGSKASDIDEFWSYHVDDGRGLARIVSLRSLCGS…
A0A2P6U325 229-377 EVHAWPAALRPHLNLASQLARDEAWQRLQQDAFARAQGRCEVTSAFLESPAAAVAPRWQCDEPARVLRLVGLRAEAPEVQQVGALLE…
A0A1P8UBF6 2-93 None
A0A2K3J5G9 10-170 None
A0A3C1DPT0 4-149 None
Q97XL4 28-211 None
A0A7S3LNI9 219-357 None
A0A5P9C0U1 149-290 None
A0A842RQE0 17-143 None
A0A0F9N373 13-143 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.