DPCstruct | MC42811

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)127 ± 9 aa
Standard deviation of domain lengths8.61
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score78.22
Mean fraction of residues predicted as intrinsically disordered0.50
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)40.73
Pfam Score83.33
Assigned Pfam label(s) PF16752- PF02466

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1L9TJE4 1-133 MGGTYEFVKTSSANLRETEDAWNVALGGFFSGAILGLRARTFPALLGHGAALATAMGAFEYTGGSLFGYKKDRDVDEFERREQLRTQ…
W2RNK1 72-202 GASYAFISTASGNLREKEDFWNHFYGGAATGALLGLRRRTFPSVIGTALFAGAVMGGLSFAGGQVYATGETPEERIARKEEHRRRFR…
R9P888 83-200 None
M7TF82 63-184 None
A0A428UEZ9 56-193 None
A0A2T4C6P2 18-146 None
C4JSP3 228-365 None
A0A425BS19 4-109 None
A0A1B5L7S0 32-162 None
A0A2S7PJN3 1-129 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.