DPCstruct | MC42777

Metacluster Properties and Pfam Annotations

Number of structural domains2800
Mean domain length (aa)233 ± 61 aa
Standard deviation of domain lengths61.08
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score86.66
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)11.75
Pfam Score95.03
Assigned Pfam label(s) PF01594- CL0015- CL0177- PF10565- PF03900

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2W4JYL1 9-175 None
A0A5A7MSE5 10-217 None
B1X315 68-406 None
A0A418RFE2 59-290 None
A0A6G8FFR5 22-229 None
A0A822XWU8 6-248 None
A0A7X0VXM0 6-155 None
A0A645I1V9 13-205 None
A0A534UEA3 3-260 None
A0A856MEG9 36-305 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.