DPCstruct | MC42777

Metacluster Properties and Pfam Annotations

Number of structural domains2800
Mean domain length (aa)233 ± 61 aa
Standard deviation of domain lengths61.08
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score86.66
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)11.75
Pfam Score95.03
Assigned Pfam label(s) PF01594- CL0015- CL0177- PF10565- PF03900

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
G9ZBH9 2-157 None
A0A4V5PJE1 173-393 None
K6SAR5 3-174 None
A0A507DYY4 18-387 None
F5L3P8 20-202 None
B7X3I6 23-227 None
B7X554 17-299 None
A0A1F5H3Y7 20-257 None
A0A7X2N4E4 2-127 None
A0A2N9NE97 10-209 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.