DPCstruct | MC42777

Metacluster Properties and Pfam Annotations

Number of structural domains2800
Mean domain length (aa)233 ± 61 aa
Standard deviation of domain lengths61.08
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score86.66
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)11.75
Pfam Score95.03
Assigned Pfam label(s) PF01594- CL0015- CL0177- PF10565- PF03900

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7W0L3C4 16-234 LGDITVFAAASLTEAFTELGELMEDEQPGTEITFNFASSSDLALQIGEGAPADVFASANPVQMEVVEDEDLAEEPVVFVTNKLVILI…
A0A381GXC7 14-171 GDKLTNNPKSRLVFLGWMDSGTRNLITKNPVEKPEDLHGMKIRVQGSPVALDTLKDMGANSVAMGVSEVFSGMQTGVIDGAENNPPT…
A0A5C1DKH3 3-127 None
I7JFC9 20-163 None
A0A1B0C6Y1 200-374 None
A0A7L5Y1P0 90-302 None
A0A7S2U9M2 1-288 None
A0A0E0GFS3 553-718 None
A0A7Y3J0K2 190-388 None
A0A2G8LE34 79-478 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.