DPCstruct | MC42768

Metacluster Properties and Pfam Annotations

Number of structural domains41
Mean domain length (aa)148 ± 23 aa
Standard deviation of domain lengths23.42
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score91.17
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.87
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)45.95
Pfam Score100.00
Assigned Pfam label(s) CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
X4ZZN4 122-275 TQMHYARKGIITPEMEFIAIRENVDPEFVRSEVASGRAIIPSNINHPESEPMIIGRNFLVKINANIGNSAVSSSIDEEVEKMRWATH…
A0A843EHY8 6-120 EEARRGITPLVKRIAEKERMSEEFVRNGIASGRIVVPCNPIHNPEPGAVGEGMSIKVNVNLGTSRDMPDLDPDLRKLDGALTSGADA…
A0A0J1FFD3 10-138 None
M6RKJ2 84-217 None
F0NNI8 3-159 None
A0A7C3XTM9 97-251 None
A0A495AAS8 95-257 None
W0IQ09 126-304 None
A0A1B0C474 154-313 None
A0A2I0D266 24-172 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.