DPCstruct | MC42731

Metacluster Properties and Pfam Annotations

Number of structural domains42
Mean domain length (aa)153 ± 32 aa
Standard deviation of domain lengths31.93
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score80.41
Mean fraction of residues predicted as intrinsically disordered0.37
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)23.11
Pfam Score97.83
Assigned Pfam label(s) PF08969- CL0366

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A822DVE2 15-153 IQWLLENQCRIPVRSTTPIHYYYKTSDTLIDQADYYYQTNQFEQSFILYSRYITLFVEELKKYHRDFPNVSINDRERVKDIIRTKAF…
A0A183PVM0 5-112 PQERLDALLKSAEDFAIIQNIDISHYARFIRSMFRLSVQFSEAGQKERAYILSIRAVLCIRELPNHNGYQRLDPRVQSELKSLGKLL…
A0A4Q2D1Y6 2-151 None
A0A0R3QBS3 10-163 None
A0A1Y1W5J9 19-145 None
A0A446NEF9 1-153 None
A0A835GU32 1-161 None
A0A6A4Q781 5-124 None
A0A5D2TLA3 8-128 None
A0A6V7PGL9 9-131 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.