DPCstruct | MC42720

Metacluster Properties and Pfam Annotations

Number of structural domains16
Mean domain length (aa)144 ± 11 aa
Standard deviation of domain lengths10.73
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score84.94
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.92
Mean intra-cluster local Distance Difference Test score0.84
Mean intra-cluster sequence similarity (%)40.44
Pfam Score100.00
Assigned Pfam label(s) PF19274

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2R8PWA3 1-138 MREMAGSWQMTVELKMGLFSETESEADPLAASEESQPFPRPPNVTPHSHWIEFLIQRFEIAKYSSADQVEIFTGLLQRALSLSVGGR…
A0A822BCC5 375-511 EEIYKVWEKIISDRHGLYSIDKLEPSPLAPSEKEELKPKPPSVKPHRIFLRFIEERVFLCMHKADIEMEMLVDLLHKSLSLILENSK…
A0A670ZGM5 1-146 None
A0A7E4RGV4 166-302 None
A0A3P7EVW6 1135-1301 None
A0A6A4V1X6 548-684 None
A0A1I8FKE5 237-377 None
A0A820BUY9 240-376 None
A0A7R9HL73 234-370 None
A0A2I4ALK9 1-146 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.