DPCstruct | MC42714

Metacluster Properties and Pfam Annotations

Number of structural domains41
Mean domain length (aa)107 ± 13 aa
Standard deviation of domain lengths13.09
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score88.90
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)29.77
Pfam Score100.00
Assigned Pfam label(s) CL0029

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1K2BQP7 1-98 MTSVDNVLRRPCAGPAVWKGPDLANSTEWVLRLSPAQTGELDAALRSVRERGLPLLKVTADDFPLPTLAGELARLTDVLENGRGFVR…
A0A1Q3E5I0 211-310 SQLPSGFPSRVEGPIVWEGKDWISEDQWVFHLSPAHLQEIDDALAHFKALNRAMGYISNDTFPLPTLSKILVSLANELYSGRGFFVL…
A0A7X1TYI3 16-139 None
A0A2P5VKL7 2-88 None
M1W1Y7 103-191 None
A0A6G1MEP2 2-106 None
A0A2V6RQ61 41-142 None
A0A1Q5QB87 309-438 None
A0A7J7Q9H9 16-116 None
A0A162LNE1 21-136 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.