DPCstruct | MC42700

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)185 ± 16 aa
Standard deviation of domain lengths15.58
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score79.15
Mean fraction of residues predicted as intrinsically disordered0.37
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)34.90
Pfam Score86.67
Assigned Pfam label(s) CL0221- CL0537

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H0EIE1 6-199 TPPQNVEATSTEVALTGGEVAPPAERKMKKIIRKKKRPARPQIDPSMMKSEPPPQTGTIFNIWYNKWSGGDREDKYLSKTAAAGRCN…
A0A7S2H0G1 125-328 KEILKRPSRKQAEQIASKNSVLEGAYEYNIWYGKFMGDHWDSKKGKDPAESRCKLLEYAGYTKADKHMNNAKFFCLFFARGCCAYGK…
G0R3J4 42-200 None
A0A7S0DTI7 8-178 None
A0A0D2N5H5 13-178 None
R1ESA2 1-178 None
A0A146I293 7-192 None
A0A1Y1YJY9 9-190 None
A0A812JG73 40-244 None
A0A2R5GTT4 115-314 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.